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DTSTAMP:20250513T155722Z
DESCRIPTION: \n\nEstablished in 1935\, the Hughlings Jackson Lecture is The
  Neuro’s premier scientific lecture. It honors the legacy of British neuro
 logist John Hughlings Jackson (1835-1911) who pioneered the development of
  neurology as a medical specialty.\n\nSpeaker: Sheena Josselyn\, PhD\n	Seni
 or Scientist\, Hospital for Sick Children & Professor\, University of Toro
 nto\, Canada\n\nAbstract: Understanding how the brain uses information is 
 a fundamental goal of neuroscience. Several human disorders (ranging from 
 autism spectrum disorder to PTSD to Alzheimer’s disease) may stem from dis
 rupted information processing. Therefore\, this basic knowledge is not onl
 y critical for understanding normal brain function but also vital for the 
 development of new treatment strategies for these disorders. The memory ma
 y be defined as the retention over time of internal representations gained
  through experience\, and the capacity to reconstruct these representation
 s at later times. Long-lasting physical brain changes (‘engrams’) are thou
 ght to encode these internal representations. The concept of a physical me
 mory trace likely originated in ancient Greece\, although it wasn’t until 
 1904 that Richard Semon first coined the term ‘engram’. Despite its long h
 istory\, finding a specific engram has been challenging\, likely because a
 n engram is encoded at multiple levels (epigenetic\, synaptic\, cell assem
 bly). My lab is interested in understanding how specific neurons are recru
 ited or allocated to an engram\, and how neuronal membership in an engram 
 may change over time or with a new experience. Here I will describe both o
 lder and new unpublished data in our efforts to understand memories in mic
 e.\n\nRegistration is available here. \n\nFor those attending virtually\, 
 you may send in your  questions for the speaker here\n\nBio: Sheena Jossel
 yn is a Senior Scientist at The Hospital for Sick Children (SickKids) and 
 a Professor in the departments of Psychology and Physiology at the Univers
 ity of Toronto in Canada. She holds a Canada Research Chair in Brain Mecha
 nisms underlying Memory and is a Fellow of the Royal Society of Canada. He
 r undergraduate degrees and a Master's degree in Clinical Psychology were 
 granted by Queen’s University in Kingston (Canada) where she worked in Dr.
  Richard Beninger’s lab. Sheena received a Ph.D. in Neuroscience/Psycholog
 y from the University of Toronto with Dr. Franco Vaccarino. She conducted 
 post-doctoral work with Dr. Mike Davis (Yale University) and Dr. Alcino Si
 lva (UCLA) before returning to Toronto. Dr. Josselyn is interested in unde
 rstanding how the brain encodes\, stores and uses information. Several hum
 an disorders (ranging from autism spectrum disorder to Alzheimer’s disease
 ) may stem from disrupted information processing. Therefore\, this basic k
 nowledge is not only critical for understanding normal brain function but 
 also vital for the development of new treatment strategies for these disor
 ders.\n\n\n \n
DTSTART:20220331T200000Z
DTEND:20220331T210000Z
LOCATION:CA\, QC\, Montreal\, Jeanne Timmins Amphitheatre\, The Neuro\, 380
 1 University Street
SUMMARY:Hughlings Jackson Lecture : Making Memories in Mice (in-person and 
 virtual)
URL:/neuro/channels/event/hughlings-jackson-lecture-ma
 king-memories-mice-person-and-virtual-334727
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